I found that chaotic characters can't use Axiomatic enchanted weapons full effects (they were not recieving bonuses or something like that) (makes sense) and I assume that evil characters can't use Holy enchanted weapons. But what about neutral characters? Are they able to use one-step away items? (i.e., Neutral Good fighter able to use a Axiomatic Holy weapon?) Thanks in advance!
Characters of the opposite alignment take a negative level when equipping aligned weapons, but those "in the middle" can use them to full effect. So a True Neutral fighter can use any weapon crafted with any bonus without suffering any ill effect.